Semaglutide Dosing & Reconstitution Chart
How many insulin-syringe units to draw for Semaglutide, based on how much bacteriostatic water you add to a 5 mg vial. Every number below is on a U-100 (100 units = 1 mL) syringe and matches our calculator.
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| Water added | Concentration | 125 mcg dose | 250 mcg dose | 375 mcg dose | 500 mcg dose |
|---|---|---|---|---|---|
| 1 mL | 5 mg/mL | 2.5 u | 5 u | 7.5 u | 10 u |
| 2 mL | 2.5 mg/mL | 5 u | 10 u | 15 u | 20 u |
| 3 mL | 1.667 mg/mL | 7.5 u | 15 u | 22.5 u | 30 u |
| 5 mL | 1 mg/mL | 12.5 u | 25 u | 37.5 u | 50 u |
Cells show units to draw on a U-100 insulin syringe.
Calculate your exact Semaglutide dose
Pre-filled with Semaglutide’s commonly cited vial and dose. Change any field to match your vial — it shows the exact units, concentration, and doses per vial.
Add 2 mL of bacteriostatic water to your 5 mg vial. That gives you about 20 doses of 250 mcg. For each dose, draw 10 units into a 100-unit insulin syringe.
Semaglutide dosing FAQ
How many units of Semaglutide should I draw?
Reconstituting a 5 mg vial of Semaglutide with 2 mL of bacteriostatic water gives 2.5 mg/mL. A 250 mcg dose is about 10 units on a U-100 insulin syringe, roughly 20 doses per vial. This is a commonly cited example for context, not medical advice.
How much bacteriostatic water do I add to Semaglutide?
There is no single correct amount. More water makes each dose a larger, easier-to-measure volume; less water makes it more concentrated. The chart above shows the units for 1–5 mL — 2 mL is a common choice for a 5 mg vial.
How many doses are in a 5 mg Semaglutide vial?
At a 250 mcg dose, a 5 mg vial holds about 20 doses. Larger doses mean fewer doses per vial, and the amount of water you add does not change this.