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Metabolic & longevity

5-Amino-1MQ

Also known as: 5-amino-1-methylquinolinium

A small molecule (not a peptide) studied for metabolism and fat loss by blocking the enzyme NNMT.

5-Amino-1MQ at a glance

Name5-Amino-1MQ
Also known as5-amino-1-methylquinolinium
CategoryMetabolic & longevity
TypeAmino / injectable
SequenceSmall-molecule NNMT inhibitor
Typical dose~50–150 mg
FrequencyDaily
RouteOral (capsule)
Half-lifeNot well characterized in humans.

Overview

5-Amino-1MQ is a small molecule popular in the peptide/longevity community. It inhibits NNMT, an enzyme that’s overactive in fat tissue and linked to slowed metabolism. Blocking it may raise cellular NAD+ and encourage fat cells to burn more energy. It’s usually taken orally.

How it’s thought to work

  • Inhibits nicotinamide N-methyltransferase (NNMT) in fat and muscle.
  • May increase NAD+ and cellular energy expenditure.

Researched uses

  • Fat loss and metabolic research
  • Longevity and muscle-function studies

Commonly cited protocol

Typical dose~50–150 mg
FrequencyDaily
RouteOral (capsule)
NotesUsually a capsule, not an injection.

Reconstitution

Typically an oral capsule, so reconstitution/syringe math does not apply.

Cautions

  • Not approved; human data are limited.
  • A research chemical, not a peptide.
  • Long-term safety unknown.

5-Amino-1MQ FAQ

What is 5-Amino-1MQ?

A small molecule (not a peptide) studied for metabolism and fat loss by blocking the enzyme NNMT.

How does 5-Amino-1MQ work?

Inhibits nicotinamide N-methyltransferase (NNMT) in fat and muscle. May increase NAD+ and cellular energy expenditure.

What is 5-Amino-1MQ used for?

Fat loss and metabolic research; Longevity and muscle-function studies.

What is a typical 5-Amino-1MQ dose?

~50–150 mg, Daily, Oral (capsule). This is a commonly cited figure for context only, not medical advice.

How do you reconstitute 5-Amino-1MQ?

Typically an oral capsule, so reconstitution/syringe math does not apply.

What is the half-life of 5-Amino-1MQ?

Not well characterized in humans.

⚠️ Educational reference only — not medical advice. These compounds are largely research chemicals not approved for human use in most countries. Nothing here is a recommendation to obtain or administer any substance. Consult a qualified clinician.