VIP
Also known as: Vasoactive Intestinal Peptide
A signaling peptide studied for inflammation, immune balance, and chronic inflammatory response syndrome (CIRS).
VIP at a glance
| Name | VIP |
|---|---|
| Also known as | Vasoactive Intestinal Peptide |
| Category | Immune & respiratory |
| Type | Peptide |
| Sequence | 28-amino-acid neuropeptide |
| Typical dose | ~50 mcg per spray (protocol-dependent) |
| Frequency | Several times daily in CIRS use |
| Route | Intranasal (common) or injection |
| Half-life | Very short (minutes). |
Overview
VIP is a naturally occurring peptide with wide-ranging roles in blood flow, immune regulation, and inflammation. In the functional-medicine world it is used intranasally as a late step in protocols for CIRS (mold/biotoxin illness). It is also studied for lung and immune conditions.
How it’s thought to work
- Activates VPAC receptors to reduce inflammation and modulate immune responses.
- Regulates blood flow and supports pulmonary and gut function.
Researched uses
- CIRS / biotoxin-illness protocols
- Inflammation and pulmonary research
Commonly cited protocol
| Typical dose | ~50 mcg per spray (protocol-dependent) |
|---|---|
| Frequency | Several times daily in CIRS use |
| Route | Intranasal (common) or injection |
| Notes | Usually used only after other CIRS steps are addressed. |
Reconstitution
Usually compounded as a nasal spray, so injection unit math generally does not apply.
Cautions
- Prescription/compounded where used.
- Can lower blood pressure and cause flushing.
- Best used under a knowledgeable clinician’s guidance.
VIP FAQ
What is VIP?
A signaling peptide studied for inflammation, immune balance, and chronic inflammatory response syndrome (CIRS).
How does VIP work?
Activates VPAC receptors to reduce inflammation and modulate immune responses. Regulates blood flow and supports pulmonary and gut function.
What is VIP used for?
CIRS / biotoxin-illness protocols; Inflammation and pulmonary research.
What is a typical VIP dose?
~50 mcg per spray (protocol-dependent), Several times daily in CIRS use, Intranasal (common) or injection. This is a commonly cited figure for context only, not medical advice.
How do you reconstitute VIP?
Usually compounded as a nasal spray, so injection unit math generally does not apply.
What is the half-life of VIP?
Very short (minutes).