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Longevity

Endoluten

Also known as: Pineal peptide bioregulator · Endoluten AA

A peptide extract derived from pineal tissue, studied in Russian bioregulator research for aging-related and neuroendocrine markers.

Endoluten at a glance

NameEndoluten
Also known asPineal peptide bioregulator, Endoluten AA
CategoryLongevity
TypePeptide
SequenceTissue-specific peptide fraction
Typical doseCommonly cited around 1-3 mg per short course
FrequencyShort cyclical courses in the discussed protocols
RouteSubcutaneous or intramuscular injection (research); oral capsule forms also marketed
Half-lifeNot well established.

Overview

Endoluten is presented in the Khavinson bioregulator literature as a peptide preparation obtained from the pineal gland. It is the most cited of the pineal-derived bioregulators and is discussed largely in the context of aging, neuroendocrine rhythm, and general longevity interest. Nearly all of the supporting work originates from a small set of Russian and Eastern-European laboratories, is older, and has not been broadly reproduced in mainstream Western literature, so any claims about it should be read with caution.

How it’s thought to work

  • Proposed to act as a tissue-specific 'peptide bioregulator' influencing gene expression in pineal and related cells.
  • Discussed in relation to melatonin-linked circadian and neuroendocrine signaling.
  • The proposed mechanisms are not well established outside the originating research group and lack independent confirmation.

Researched uses

  • General 'anti-aging' and longevity research interest
  • Neuroendocrine and circadian-rhythm markers in aging models
  • Cited in discussions of pineal function and age-related decline

Commonly cited protocol

Typical doseCommonly cited around 1-3 mg per short course
FrequencyShort cyclical courses in the discussed protocols
RouteSubcutaneous or intramuscular injection (research); oral capsule forms also marketed
NotesTypically described as repeated in cycles rather than continuously in the source literature.

Reconstitution

Commonly a 5-10 mg vial; reconstitute with bacteriostatic water and use the calculator for units.

Endoluten dosage calculator

The calculator below is pre-filled with Endoluten’s commonly cited vial size and dose. Adjust the vial amount, bacteriostatic water, or dose to match your own vial — it will show the exact insulin-syringe units to draw, the concentration, and how many doses the vial holds.

mg
mL
How much water you add is your choice — it doesn’t change your dose, only how many units you draw. Common:
Draw to
40 units
= 0.4 mL on a 1 mL (100 units) syringe
40 units0100
Concentration
5 mg/mL
Per unit
50 mcg/u
Doses per vial
5 × 2mg
Volume
0.4 mL
📋 In plain English

Add 2 mL of bacteriostatic water to your 10 mg vial. That gives you about 5 doses of 2 mg. For each dose, draw 40 units into a 100-unit insulin syringe.

See the full Endoluten dosing chart (units for every dose & water amount), or open the full peptide calculator →

Cautions

  • Not FDA-approved; considered a research compound, not an approved therapy.
  • The evidence base is limited, older, and largely non-Western, and has not been widely replicated.
  • Purity and true content of research-grade or extract-based material vary considerably by source.
  • Not a substitute for evaluation or care from a qualified clinician.

Endoluten FAQ

What is Endoluten?

A peptide extract derived from pineal tissue, studied in Russian bioregulator research for aging-related and neuroendocrine markers.

How does Endoluten work?

Proposed to act as a tissue-specific 'peptide bioregulator' influencing gene expression in pineal and related cells. Discussed in relation to melatonin-linked circadian and neuroendocrine signaling. The proposed mechanisms are not well established outside the originating research group and lack independent confirmation.

What is Endoluten used for?

General 'anti-aging' and longevity research interest; Neuroendocrine and circadian-rhythm markers in aging models; Cited in discussions of pineal function and age-related decline.

What is a typical Endoluten dose?

Commonly cited around 1-3 mg per short course, Short cyclical courses in the discussed protocols, Subcutaneous or intramuscular injection (research); oral capsule forms also marketed. This is a commonly cited figure for context only, not medical advice.

How do you reconstitute Endoluten?

Commonly a 5-10 mg vial; reconstitute with bacteriostatic water and use the calculator for units.

What is the half-life of Endoluten?

Not well established.

Related longevity peptides

⚠️ Educational reference only — not medical advice. These compounds are largely research chemicals not approved for human use in most countries. Nothing here is a recommendation to obtain or administer any substance. Consult a qualified clinician.