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Longevity

Vesugen

Also known as: Vesugen bioregulator · Vascular peptide

A short synthetic tripeptide bioregulator from Russian research, studied for vascular tissue support.

Vesugen at a glance

NameVesugen
Also known asVesugen bioregulator, Vascular peptide
CategoryLongevity
TypePeptide
SequenceLys-Glu-Asp
Typical dose~2-5 mg per day
FrequencyOnce daily over short courses in reported use
RouteIntramuscular injection (research)
Half-lifeVery short; small peptides clear rapidly.

Overview

Vesugen is a synthetic tripeptide (lysine-glutamic acid-aspartic acid) developed as a vascular-directed bioregulator in Khavinson's peptide program. It is commonly cited in that literature for context on the health of blood vessel walls and age-related vascular changes. The supporting evidence is largely non-Western, limited, and not broadly replicated, so it should be viewed as preliminary.

How it’s thought to work

  • Proposed to act as a tissue-specific bioregulator for vascular cells.
  • Reported to influence endothelial cell function in Russian studies.
  • Suggested to modulate expression of genes relevant to vessel maintenance.
  • Described as supporting normal vascular tone and structure.

Researched uses

  • Vascular aging research
  • Endothelial function studies
  • Circulatory support in Russian reports
  • General geroprotection research

Commonly cited protocol

Typical dose~2-5 mg per day
FrequencyOnce daily over short courses in reported use
RouteIntramuscular injection (research)
NotesSupplied as a lyophilized powder in original formulations.

Reconstitution

Commonly a 5 mg vial; 5 mg in 2 mL gives 2.5 mg/mL, so a 2 mg dose is about 16 units on a U-100 syringe.

Vesugen dosage calculator

The calculator below is pre-filled with Vesugen’s commonly cited vial size and dose. Adjust the vial amount, bacteriostatic water, or dose to match your own vial — it will show the exact insulin-syringe units to draw, the concentration, and how many doses the vial holds.

mg
mL
How much water you add is your choice — it doesn’t change your dose, only how many units you draw. Common:
Draw to
80 units
= 0.8 mL on a 1 mL (100 units) syringe
80 units0100
Concentration
2.5 mg/mL
Per unit
25 mcg/u
Doses per vial
2 × 2000mcg
Volume
0.8 mL
📋 In plain English

Add 2 mL of bacteriostatic water to your 5 mg vial. That gives you about 2 doses of 2000 mcg. For each dose, draw 80 units into a 100-unit insulin syringe.

See the full Vesugen dosing chart (units for every dose & water amount), or open the full peptide calculator →

Cautions

  • Not FDA-approved; a research chemical outside its origin countries.
  • Human evidence is limited and largely non-Western.
  • Long-term safety is not established.
  • Source purity varies.

Vesugen FAQ

What is Vesugen?

A short synthetic tripeptide bioregulator from Russian research, studied for vascular tissue support.

How does Vesugen work?

Proposed to act as a tissue-specific bioregulator for vascular cells. Reported to influence endothelial cell function in Russian studies. Suggested to modulate expression of genes relevant to vessel maintenance. Described as supporting normal vascular tone and structure.

What is Vesugen used for?

Vascular aging research; Endothelial function studies; Circulatory support in Russian reports; General geroprotection research.

What is a typical Vesugen dose?

~2-5 mg per day, Once daily over short courses in reported use, Intramuscular injection (research). This is a commonly cited figure for context only, not medical advice.

How do you reconstitute Vesugen?

Commonly a 5 mg vial; 5 mg in 2 mL gives 2.5 mg/mL, so a 2 mg dose is about 16 units on a U-100 syringe.

What is the half-life of Vesugen?

Very short; small peptides clear rapidly.

Related longevity peptides

⚠️ Educational reference only — not medical advice. These compounds are largely research chemicals not approved for human use in most countries. Nothing here is a recommendation to obtain or administer any substance. Consult a qualified clinician.