N-Acetyl Selank
Also known as: N-Acetyl Selank Amidate · NA-Selank
An acetylated analog of Selank, commonly cited in the research literature for context around anxiety and cognition.
N-Acetyl Selank at a glance
| Name | N-Acetyl Selank |
|---|---|
| Also known as | N-Acetyl Selank Amidate, NA-Selank |
| Category | Cognitive & neuroprotective |
| Type | Peptide |
| Sequence | N-acetylated analog of Selank, a synthetic heptapeptide based on the immunomodulator tuftsin |
| Typical dose | ~250-900 mcg per day (commonly cited) |
| Frequency | Once daily or divided into two or three applications |
| Route | Intranasal (research) |
| Half-life | Reported longer than unmodified Selank, still relatively short (hours). |
Overview
N-Acetyl Selank is a modified form of Selank, a synthetic peptide derived from the endogenous tetrapeptide tuftsin. The acetylation is described as intended to increase stability. As with Semax, most data originate from Russian research settings, and large-scale international clinical trials are absent. Included for educational context only.
How it’s thought to work
- Reported to modulate GABAergic and serotonergic signaling.
- Appears to influence expression of brain-derived neurotrophic factor (BDNF).
- Studied for effects on the balance of pro- and anti-inflammatory cytokines.
Researched uses
- Anxiety-like behavior in animal and early human studies
- Cognitive and memory support in exploratory research
- Stress resilience and mood regulation
Commonly cited protocol
| Typical dose | ~250-900 mcg per day (commonly cited) |
|---|---|
| Frequency | Once daily or divided into two or three applications |
| Route | Intranasal (research) |
| Notes | Applied as nasal drops or spray; the acetyl form is cited as more stable than plain Selank. |
Reconstitution
Typically sold as a ready-to-use intranasal solution, so injection unit math does not apply.
Cautions
- Not FDA-approved; classified as a research chemical in most markets.
- Evidence base is largely limited to Russian studies.
- Concentration and purity differ between suppliers.
- Long-term safety is not established.
N-Acetyl Selank FAQ
What is N-Acetyl Selank?
An acetylated analog of Selank, commonly cited in the research literature for context around anxiety and cognition.
How does N-Acetyl Selank work?
Reported to modulate GABAergic and serotonergic signaling. Appears to influence expression of brain-derived neurotrophic factor (BDNF). Studied for effects on the balance of pro- and anti-inflammatory cytokines.
What is N-Acetyl Selank used for?
Anxiety-like behavior in animal and early human studies; Cognitive and memory support in exploratory research; Stress resilience and mood regulation.
What is a typical N-Acetyl Selank dose?
~250-900 mcg per day (commonly cited), Once daily or divided into two or three applications, Intranasal (research). This is a commonly cited figure for context only, not medical advice.
How do you reconstitute N-Acetyl Selank?
Typically sold as a ready-to-use intranasal solution, so injection unit math does not apply.
What is the half-life of N-Acetyl Selank?
Reported longer than unmodified Selank, still relatively short (hours).