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Cognitive & neuroprotective

Dihexa

Also known as: N-hexanoic-Tyr-Ile-(6) aminohexanoic amide · PNB-0408

A potent nootropic peptide studied for forming new synaptic connections and supporting memory.

Dihexa at a glance

NameDihexa
Also known asN-hexanoic-Tyr-Ile-(6) aminohexanoic amide, PNB-0408
CategoryCognitive & neuroprotective
TypePeptide
SequenceModified angiotensin IV analog
Typical doseSmall (research-scale)
FrequencyVaries
RouteOral or transdermal (research)
Half-lifeNot well characterized.

Overview

Dihexa is a small, potent compound derived from angiotensin IV, researched for its striking ability to promote new synapse formation in the brain. Animal work has looked at it for memory and neurodegenerative models; human data are very limited.

How it’s thought to work

  • Enhances hepatocyte growth factor (HGF)/c-Met signaling tied to synapse growth.
  • Promotes formation of new synaptic connections (synaptogenesis).

Researched uses

  • Memory and cognition research
  • Neurodegeneration models

Commonly cited protocol

Typical doseSmall (research-scale)
FrequencyVaries
RouteOral or transdermal (research)
NotesExtremely potent in animal studies; human dosing is not established.

Reconstitution

Usually taken orally/transdermally, so injection unit math generally does not apply.

Cautions

  • Not approved; minimal human safety data.
  • Its strong pro-growth effects on neurons are not fully understood long-term.
  • Research chemical status.

Dihexa FAQ

What is Dihexa?

A potent nootropic peptide studied for forming new synaptic connections and supporting memory.

How does Dihexa work?

Enhances hepatocyte growth factor (HGF)/c-Met signaling tied to synapse growth. Promotes formation of new synaptic connections (synaptogenesis).

What is Dihexa used for?

Memory and cognition research; Neurodegeneration models.

What is a typical Dihexa dose?

Small (research-scale), Varies, Oral or transdermal (research). This is a commonly cited figure for context only, not medical advice.

How do you reconstitute Dihexa?

Usually taken orally/transdermally, so injection unit math generally does not apply.

What is the half-life of Dihexa?

Not well characterized.

Related cognitive & neuroprotective peptides

⚠️ Educational reference only — not medical advice. These compounds are largely research chemicals not approved for human use in most countries. Nothing here is a recommendation to obtain or administer any substance. Consult a qualified clinician.