CJC-1295 without DAC
Also known as: Mod GRF 1-29 · Modified GRF(1-29) · CJC-1295 DAC-free
A short-acting GHRH fragment that stimulates a natural growth-hormone pulse — the "DAC-free" version clears quickly and is frequently paired with a GHRP.
CJC-1295 without DAC at a glance
| Name | CJC-1295 without DAC |
|---|---|
| Also known as | Mod GRF 1-29, Modified GRF(1-29), CJC-1295 DAC-free |
| Category | Growth-hormone axis |
| Type | Peptide |
| Sequence | Modified GRF(1-29) — a 29-amino-acid GHRH fragment with stabilizing substitutions |
| Typical dose | ~100 mcg per dose |
| Frequency | One to three times daily, often before bed and/or post-workout |
| Route | Subcutaneous injection |
| Half-life | Short — about 30 minutes (the key difference from the DAC version). |
Overview
CJC-1295 comes in two forms. With DAC (Drug Affinity Complex) it binds albumin and lingers for days; without DAC — the version described here, also called Mod GRF 1-29 — it acts fast and washes out within about half an hour. That short window is the point: it mimics the body's own brief GHRH bursts, so researchers often combine it with a growth-hormone-releasing peptide (such as ipamorelin) that works through a complementary pathway for a larger, more natural pulse.
How it’s thought to work
- Activates pituitary GHRH receptors to trigger a short, natural-shaped GH pulse.
- Stabilizing amino-acid swaps resist the enzyme (DPP-IV) that degrades native GHRH.
- Synergizes with GHRP/ghrelin-mimetic peptides that release GH by a separate route.
Researched uses
- Raising endogenous GH/IGF-1 in research contexts
- Commonly studied stacked with ipamorelin or GHRP-2/6
Commonly cited protocol
| Typical dose | ~100 mcg per dose |
|---|---|
| Frequency | One to three times daily, often before bed and/or post-workout |
| Route | Subcutaneous injection |
| Notes | Timed away from food/fat, which can blunt the GH response in research. |
Reconstitution
Often a 5 mg vial. Reconstituting 5 mg with 2.5 mL of bacteriostatic water gives 2 mg/mL, so 100 mcg = 5 units on a U-100 syringe.
CJC-1295 without DAC dosage calculator
The calculator below is pre-filled with CJC-1295 without DAC’s commonly cited vial size and dose. Adjust the vial amount, bacteriostatic water, or dose to match your own vial — it will show the exact insulin-syringe units to draw, the concentration, and how many doses the vial holds.
Add 2.5 mL of bacteriostatic water to your 5 mg vial. That gives you about 50 doses of 100 mcg. For each dose, draw 5 units into a 100-unit insulin syringe.
See the full CJC-1295 without DAC dosing chart (units for every dose & water amount), or open the full peptide calculator →
Cautions
- Not approved for human use; research chemical status.
- Water retention, tingling or head-rush are commonly reported in anecdotal use.
- Do not confuse with the long-acting "with DAC" version — dosing logic differs.
CJC-1295 without DAC FAQ
What is CJC-1295 without DAC?
A short-acting GHRH fragment that stimulates a natural growth-hormone pulse — the "DAC-free" version clears quickly and is frequently paired with a GHRP.
How does CJC-1295 without DAC work?
Activates pituitary GHRH receptors to trigger a short, natural-shaped GH pulse. Stabilizing amino-acid swaps resist the enzyme (DPP-IV) that degrades native GHRH. Synergizes with GHRP/ghrelin-mimetic peptides that release GH by a separate route.
What is CJC-1295 without DAC used for?
Raising endogenous GH/IGF-1 in research contexts; Commonly studied stacked with ipamorelin or GHRP-2/6.
What is a typical CJC-1295 without DAC dose?
~100 mcg per dose, One to three times daily, often before bed and/or post-workout, Subcutaneous injection. This is a commonly cited figure for context only, not medical advice.
How do you reconstitute CJC-1295 without DAC?
Often a 5 mg vial. Reconstituting 5 mg with 2.5 mL of bacteriostatic water gives 2 mg/mL, so 100 mcg = 5 units on a U-100 syringe.
What is the half-life of CJC-1295 without DAC?
Short — about 30 minutes (the key difference from the DAC version).