Sigumir
Also known as: Cartilage peptide bioregulator · Bone-joint bioregulator
A cartilage/bone-derived peptide bioregulator studied in Russian research for joint- and bone-tissue markers.
Sigumir at a glance
| Name | Sigumir |
|---|---|
| Also known as | Cartilage peptide bioregulator, Bone-joint bioregulator |
| Category | Recovery & tissue repair |
| Type | Peptide |
| Sequence | Tissue-specific peptide fraction |
| Typical dose | Commonly cited around 1-3 mg per short course |
| Frequency | Short cyclical courses in the discussed protocols |
| Route | Subcutaneous or intramuscular injection (research); oral capsule forms also marketed |
| Half-life | Not well established. |
Overview
Sigumir is presented in the bioregulator literature as a peptide preparation derived from cartilage and bone tissue, discussed in the context of joint maintenance and age-related musculoskeletal changes. It is often grouped with recovery-oriented bioregulators. As with the rest of the catalogue, the supporting research is concentrated in the originating Russian group, is older and non-Western, and has not been broadly validated in independent orthopedic or rheumatology literature.
How it’s thought to work
- Proposed to act as a cartilage/bone-specific peptide bioregulator influencing gene expression in connective tissue.
- Discussed in relation to maintenance of chondrocyte and bone-cell function with age.
- Mechanistic claims derive mainly from in-house studies and are not well established externally.
Researched uses
- Joint- and cartilage-tissue research interest
- Age-related musculoskeletal maintenance discussions
- Cited alongside other organ-specific bioregulators
Commonly cited protocol
| Typical dose | Commonly cited around 1-3 mg per short course |
|---|---|
| Frequency | Short cyclical courses in the discussed protocols |
| Route | Subcutaneous or intramuscular injection (research); oral capsule forms also marketed |
| Notes | Described as used in repeated cycles in the source literature. |
Reconstitution
Commonly a 5-10 mg vial; reconstitute with bacteriostatic water and use the calculator for units.
Sigumir dosage calculator
The calculator below is pre-filled with Sigumir’s commonly cited vial size and dose. Adjust the vial amount, bacteriostatic water, or dose to match your own vial — it will show the exact insulin-syringe units to draw, the concentration, and how many doses the vial holds.
Add 2 mL of bacteriostatic water to your 10 mg vial. That gives you about 5 doses of 2 mg. For each dose, draw 40 units into a 100-unit insulin syringe.
See the full Sigumir dosing chart (units for every dose & water amount), or open the full peptide calculator →
Cautions
- Not FDA-approved; a research compound, not an approved treatment for joint or bone conditions.
- Human evidence is limited, older, and largely non-Western, and has not been widely replicated.
- Research-grade material varies in purity and true content by source.
- Joint and bone problems should be evaluated by a qualified clinician rather than self-directed peptide use.
Sigumir FAQ
What is Sigumir?
A cartilage/bone-derived peptide bioregulator studied in Russian research for joint- and bone-tissue markers.
How does Sigumir work?
Proposed to act as a cartilage/bone-specific peptide bioregulator influencing gene expression in connective tissue. Discussed in relation to maintenance of chondrocyte and bone-cell function with age. Mechanistic claims derive mainly from in-house studies and are not well established externally.
What is Sigumir used for?
Joint- and cartilage-tissue research interest; Age-related musculoskeletal maintenance discussions; Cited alongside other organ-specific bioregulators.
What is a typical Sigumir dose?
Commonly cited around 1-3 mg per short course, Short cyclical courses in the discussed protocols, Subcutaneous or intramuscular injection (research); oral capsule forms also marketed. This is a commonly cited figure for context only, not medical advice.
How do you reconstitute Sigumir?
Commonly a 5-10 mg vial; reconstitute with bacteriostatic water and use the calculator for units.
What is the half-life of Sigumir?
Not well established.