FGL (FG Loop Peptide)
Also known as: FG Loop Peptide · FGL(L) · NCAM-derived peptide
A peptide derived from the neural cell adhesion molecule, commonly cited in the research literature for context around plasticity and memory.
FGL (FG Loop Peptide) at a glance
| Name | FGL (FG Loop Peptide) |
|---|---|
| Also known as | FG Loop Peptide, FGL(L), NCAM-derived peptide |
| Category | Cognitive & neuroprotective |
| Type | Peptide |
| Sequence | Peptide derived from the second fibronectin type III module of neural cell adhesion molecule (NCAM) |
| Typical dose | ~1-5 mg (figures extrapolated from animal work) |
| Frequency | Intermittent dosing in studies |
| Route | Subcutaneous injection (research) |
| Half-life | Not well established in humans; described as short. |
Overview
FGL (FG Loop peptide) is a synthetic peptide corresponding to a region of the neural cell adhesion molecule (NCAM). In animal research it has been examined for effects on synaptic plasticity and memory. Human evidence is minimal and it has no approved use; the information here is for educational context only.
How it’s thought to work
- Reported to activate the fibroblast growth factor receptor (FGFR).
- Appears to promote synaptic plasticity and neurite outgrowth.
- Studied for anti-inflammatory and neuroprotective effects in the brain.
Researched uses
- Learning and memory in rodent models
- Neuroprotection in models of injury and aging
- Reduction of neuroinflammation in animal studies
Commonly cited protocol
| Typical dose | ~1-5 mg (figures extrapolated from animal work) |
|---|---|
| Frequency | Intermittent dosing in studies |
| Route | Subcutaneous injection (research) |
| Notes | Human dosing has not been established; some early studies used intranasal and injectable routes. |
Reconstitution
For a 10 mg vial reconstituted with 2 mL, the concentration is 5 mg/mL, so a 1 mg dose is about 20 units on a U-100 syringe.
FGL (FG Loop Peptide) dosage calculator
The calculator below is pre-filled with FGL (FG Loop Peptide)’s commonly cited vial size and dose. Adjust the vial amount, bacteriostatic water, or dose to match your own vial — it will show the exact insulin-syringe units to draw, the concentration, and how many doses the vial holds.
Add 2 mL of bacteriostatic water to your 10 mg vial. That gives you about 10 doses of 1 mg. For each dose, draw 20 units into a 100-unit insulin syringe.
See the full FGL (FG Loop Peptide) dosing chart (units for every dose & water amount), or open the full peptide calculator →
Cautions
- Not FDA-approved; a research-stage compound.
- Human clinical data are very limited.
- Dosing figures are speculative.
- Source purity is not guaranteed.
FGL (FG Loop Peptide) FAQ
What is FGL (FG Loop Peptide)?
A peptide derived from the neural cell adhesion molecule, commonly cited in the research literature for context around plasticity and memory.
How does FGL (FG Loop Peptide) work?
Reported to activate the fibroblast growth factor receptor (FGFR). Appears to promote synaptic plasticity and neurite outgrowth. Studied for anti-inflammatory and neuroprotective effects in the brain.
What is FGL (FG Loop Peptide) used for?
Learning and memory in rodent models; Neuroprotection in models of injury and aging; Reduction of neuroinflammation in animal studies.
What is a typical FGL (FG Loop Peptide) dose?
~1-5 mg (figures extrapolated from animal work), Intermittent dosing in studies, Subcutaneous injection (research). This is a commonly cited figure for context only, not medical advice.
How do you reconstitute FGL (FG Loop Peptide)?
For a 10 mg vial reconstituted with 2 mL, the concentration is 5 mg/mL, so a 1 mg dose is about 20 units on a U-100 syringe.
What is the half-life of FGL (FG Loop Peptide)?
Not well established in humans; described as short.