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Growth-hormone axis

GHRP-6

A growth-hormone-releasing peptide known for a strong GH pulse and a pronounced hunger increase.

GHRP-6 at a glance

NameGHRP-6
CategoryGrowth-hormone axis
TypePeptide
SequenceHexapeptide GH secretagogue
Typical dose~100–200 mcg
Frequency1–3× daily
RouteSubcutaneous injection
Half-lifeShort (~30 minutes).

Overview

GHRP-6 is an older GH secretagogue similar to GHRP-2 but with a more noticeable appetite spike, driven by its ghrelin-like activity. That hunger effect is sometimes used deliberately (e.g., to support eating) and sometimes an unwanted side effect.

How it’s thought to work

  • Activates the ghrelin/GH-secretagogue receptor to release GH.
  • Strongly stimulates appetite (ghrelin-mimetic).

Researched uses

  • Raising endogenous GH/IGF-1
  • Appetite support research

Commonly cited protocol

Typical dose~100–200 mcg
Frequency1–3× daily
RouteSubcutaneous injection
NotesOften stacked with a GHRH.

Reconstitution

Often a 5 mg vial. 5 mg with 2 mL water = 2.5 mg/mL, so 100 mcg = 4 units on a U-100 syringe.

GHRP-6 dosage calculator

The calculator below is pre-filled with GHRP-6’s commonly cited vial size and dose. Adjust the vial amount, bacteriostatic water, or dose to match your own vial — it will show the exact insulin-syringe units to draw, the concentration, and how many doses the vial holds.

mg
100 mcg = 0.1 mg
mL
How much water you add is your choice — it doesn’t change your dose, only how many units you draw. Common:
Draw to
10 units
= 0.1 mL on a 1 mL (100 units) syringe
010203040506070809010010 ufill to the 10 u line on a 100-unit barrel
Concentration
1 mg/mL
Per unit
10 mcg/u
Doses per vial
50 × 100mcg
Volume
0.1 mL
📋 In plain English

Add 5 mL of bacteriostatic water to your 5 mg vial. That gives you about 50 doses of 100 mcg. For each dose, draw 10 units into a 100-unit insulin syringe.

See the full GHRP-6 dosing chart (units for every dose & water amount), or open the full peptide calculator →

Cautions

  • Not approved for human use.
  • Marked hunger; possible cortisol/prolactin rise.
  • Caution with active cancer.

GHRP-6 FAQ

What is GHRP-6?

A growth-hormone-releasing peptide known for a strong GH pulse and a pronounced hunger increase.

How does GHRP-6 work?

Activates the ghrelin/GH-secretagogue receptor to release GH. Strongly stimulates appetite (ghrelin-mimetic).

What is GHRP-6 used for?

Raising endogenous GH/IGF-1; Appetite support research.

What is a typical GHRP-6 dose?

~100–200 mcg, 1–3× daily, Subcutaneous injection. This is a commonly cited figure for context only, not medical advice.

How do you reconstitute GHRP-6?

Often a 5 mg vial. 5 mg with 2 mL water = 2.5 mg/mL, so 100 mcg = 4 units on a U-100 syringe.

What is the half-life of GHRP-6?

Short (~30 minutes).

Related growth-hormone axis peptides

⚠️ Educational reference only — not medical advice. These compounds are largely research chemicals not approved for human use in most countries. Nothing here is a recommendation to obtain or administer any substance. Consult a qualified clinician.