Matrixyl 3000
Also known as: Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7 blend
A topical cosmetic peptide blend commonly cited in the skincare literature for context on wrinkle-appearance formulations.
Matrixyl 3000 at a glance
| Name | Matrixyl 3000 |
|---|---|
| Also known as | Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7 blend |
| Category | Skin & cosmetic |
| Type | Peptide |
| Sequence | Cosmetic blend of Palmitoyl Tripeptide-1 (Pal-GHK) and Palmitoyl Tetrapeptide-7 (Pal-GQPR). |
| Typical dose | Commonly used around 3-10% of the finished cosmetic formula (the raw blend is heavily diluted) |
| Frequency | Applied once or twice daily as a cosmetic |
| Route | Topical |
| Half-life | Not typically characterized; applied topically rather than dosed systemically. |
Overview
Matrixyl 3000 is a trademarked cosmetic complex combining two matrikine-mimetic palmitoylated peptides. It is marketed for the appearance of fine lines and skin firmness, with supporting data drawn mainly from manufacturer studies and skin-model work.
How it’s thought to work
- Combines two matrikine-mimetic peptides that signal skin-repair pathways.
- Reported to encourage extracellular-matrix components such as collagen in skin models.
- Palmitoyl tails aid topical penetration.
- The two peptides are described as acting synergistically in the blend.
Researched uses
- Cosmetic wrinkle-appearance products
- Skin-firmness and elasticity formulations
- Anti-aging serums and creams
- Combination peptide skincare research
Commonly cited protocol
| Typical dose | Commonly used around 3-10% of the finished cosmetic formula (the raw blend is heavily diluted) |
|---|---|
| Frequency | Applied once or twice daily as a cosmetic |
| Route | Topical |
| Notes | A leave-on topical complex, not an injectable. |
Reconstitution
Sold as a cosmetic raw material or within finished skincare, so injection reconstitution and syringe unit math do not apply.
Cautions
- A cosmetic complex, not an approved drug.
- Much of the supporting evidence is manufacturer-generated.
- Not intended for injection.
- Provided for education only, not as a recommendation.
Matrixyl 3000 FAQ
What is Matrixyl 3000?
A topical cosmetic peptide blend commonly cited in the skincare literature for context on wrinkle-appearance formulations.
How does Matrixyl 3000 work?
Combines two matrikine-mimetic peptides that signal skin-repair pathways. Reported to encourage extracellular-matrix components such as collagen in skin models. Palmitoyl tails aid topical penetration. The two peptides are described as acting synergistically in the blend.
What is Matrixyl 3000 used for?
Cosmetic wrinkle-appearance products; Skin-firmness and elasticity formulations; Anti-aging serums and creams; Combination peptide skincare research.
What is a typical Matrixyl 3000 dose?
Commonly used around 3-10% of the finished cosmetic formula (the raw blend is heavily diluted), Applied once or twice daily as a cosmetic, Topical. This is a commonly cited figure for context only, not medical advice.
How do you reconstitute Matrixyl 3000?
Sold as a cosmetic raw material or within finished skincare, so injection reconstitution and syringe unit math do not apply.
What is the half-life of Matrixyl 3000?
Not typically characterized; applied topically rather than dosed systemically.