Palmitoyl Tripeptide-1
Also known as: Pal-GHK · Palmitoyl Oligopeptide
A topical cosmetic peptide studied for skin firmness and tone appearance.
Palmitoyl Tripeptide-1 at a glance
| Name | Palmitoyl Tripeptide-1 |
|---|---|
| Also known as | Pal-GHK, Palmitoyl Oligopeptide |
| Category | Skin & cosmetic |
| Type | Peptide |
| Sequence | Palmitoylated tripeptide (palmitoyl-Gly-His-Lys). |
| Typical dose | Typically formulated at low percentages (often well under 1% active) in leave-on products |
| Frequency | Typically applied once or twice daily |
| Route | Topical |
| Half-life | Not typically characterized for topical cosmetic use. |
Overview
Palmitoyl Tripeptide-1 is a lipidated tripeptide often paired with Palmitoyl Tetrapeptide-7 in cosmetic blends. It is marketed to support the look of firmer, more even-toned skin. It is a cosmetic ingredient rather than a medical treatment.
How it’s thought to work
- Proposed to signal skin cells toward collagen-related support.
- The palmitoyl chain is intended to enhance skin penetration.
- Functions as a cosmetic conditioning agent at the surface of the skin.
Researched uses
- Appearance of skin firmness and elasticity
- Cosmetic anti-aging and tone-evening formulations
- Serums and creams targeting fine lines
Commonly cited protocol
| Typical dose | Typically formulated at low percentages (often well under 1% active) in leave-on products |
|---|---|
| Frequency | Typically applied once or twice daily |
| Route | Topical |
| Notes | Commonly combined with other peptides in cosmetic serums; not injected. |
Reconstitution
Not applicable - this is a topical cosmetic ingredient, so injection unit math does not apply.
Cautions
- A cosmetic ingredient, not a medical treatment.
- Supporting evidence is limited and often industry-sourced.
- May cause local irritation in sensitive individuals; patch testing is common.
Palmitoyl Tripeptide-1 FAQ
What is Palmitoyl Tripeptide-1?
A topical cosmetic peptide studied for skin firmness and tone appearance.
How does Palmitoyl Tripeptide-1 work?
Proposed to signal skin cells toward collagen-related support. The palmitoyl chain is intended to enhance skin penetration. Functions as a cosmetic conditioning agent at the surface of the skin.
What is Palmitoyl Tripeptide-1 used for?
Appearance of skin firmness and elasticity; Cosmetic anti-aging and tone-evening formulations; Serums and creams targeting fine lines.
What is a typical Palmitoyl Tripeptide-1 dose?
Typically formulated at low percentages (often well under 1% active) in leave-on products, Typically applied once or twice daily, Topical. This is a commonly cited figure for context only, not medical advice.
How do you reconstitute Palmitoyl Tripeptide-1?
Not applicable - this is a topical cosmetic ingredient, so injection unit math does not apply.
What is the half-life of Palmitoyl Tripeptide-1?
Not typically characterized for topical cosmetic use.