Noopept
Also known as: N-phenylacetyl-L-prolylglycine ethyl ester · GVS-111 · Omberacetam
A synthetic dipeptide-derived nootropic, commonly cited in the research literature for context around memory and cognition.
Noopept at a glance
| Name | Noopept |
|---|---|
| Also known as | N-phenylacetyl-L-prolylglycine ethyl ester, GVS-111, Omberacetam |
| Category | Cognitive & neuroprotective |
| Type | Peptide |
| Sequence | Dipeptide-derived nootropic (N-phenylacetyl-L-prolylglycine ethyl ester) |
| Typical dose | ~10-30 mg per day (commonly cited) |
| Frequency | Split into two or three doses |
| Route | Oral (research) |
| Half-life | Short, reported at roughly 30-60 minutes for the parent compound. |
Overview
Noopept is a synthetic compound structurally related to the racetam family but built on a proline-glycine dipeptide backbone. It has been studied primarily in Russian research settings for memory and neuroprotection. It is sold as a dietary supplement in some countries and is unregulated or restricted in others. Presented for educational context only.
How it’s thought to work
- Reported to increase expression of nerve growth factor (NGF) and BDNF.
- Appears to modulate glutamatergic AMPA and NMDA receptor activity.
- Studied for antioxidant effects and reduction of excitotoxicity.
Researched uses
- Memory and learning in animal and early human studies
- Cognitive recovery after injury in exploratory research
- Anxiety and mild cognitive impairment
Commonly cited protocol
| Typical dose | ~10-30 mg per day (commonly cited) |
|---|---|
| Frequency | Split into two or three doses |
| Route | Oral (research) |
| Notes | Taken orally as tablets, capsules, or sublingual powder; cited as far more potent by weight than piracetam. |
Reconstitution
Taken orally rather than injected, so insulin-syringe unit math does not apply.
Cautions
- Not FDA-approved; regulatory status varies from supplement to controlled substance by country.
- Human clinical data are limited and mostly regional.
- Long-term safety is not well established.
- Product purity varies by supplier.
Noopept FAQ
What is Noopept?
A synthetic dipeptide-derived nootropic, commonly cited in the research literature for context around memory and cognition.
How does Noopept work?
Reported to increase expression of nerve growth factor (NGF) and BDNF. Appears to modulate glutamatergic AMPA and NMDA receptor activity. Studied for antioxidant effects and reduction of excitotoxicity.
What is Noopept used for?
Memory and learning in animal and early human studies; Cognitive recovery after injury in exploratory research; Anxiety and mild cognitive impairment.
What is a typical Noopept dose?
~10-30 mg per day (commonly cited), Split into two or three doses, Oral (research). This is a commonly cited figure for context only, not medical advice.
How do you reconstitute Noopept?
Taken orally rather than injected, so insulin-syringe unit math does not apply.
What is the half-life of Noopept?
Short, reported at roughly 30-60 minutes for the parent compound.