Palmitoyl Tetrapeptide-7
Also known as: Rigin · Pal-GQPR
A palmitoylated cosmetic peptide commonly cited in the skincare literature for context on soothing and anti-aging formulations.
Palmitoyl Tetrapeptide-7 at a glance
| Name | Palmitoyl Tetrapeptide-7 |
|---|---|
| Also known as | Rigin, Pal-GQPR |
| Category | Skin & cosmetic |
| Type | Peptide |
| Sequence | Palmitoyl-Gly-Gln-Pro-Arg |
| Typical dose | Typically formulated at very low percentages (parts-per-million range) in creams and serums |
| Frequency | Applied once or twice daily as a cosmetic |
| Route | Topical |
| Half-life | Not typically characterized; used topically rather than systemically. |
Overview
Palmitoyl Tetrapeptide-7 pairs the GQPR peptide with a palmitic-acid tail to aid skin penetration in topical products. It is used in cosmetics and is often marketed for reducing the appearance of inflammation-related aging, based largely on in vitro and formulation data.
How it’s thought to work
- The palmitoyl tail improves lipid-layer penetration of the peptide.
- Reported to modulate interleukin signaling associated with skin inflammation.
- May support extracellular-matrix maintenance in skin models.
- Frequently combined with Palmitoyl Tripeptide-1 in blends.
Researched uses
- Cosmetic anti-aging formulations
- Soothing / anti-redness skincare
- Skin-firmness appearance studies
- Combination cosmetic peptide products
Commonly cited protocol
| Typical dose | Typically formulated at very low percentages (parts-per-million range) in creams and serums |
|---|---|
| Frequency | Applied once or twice daily as a cosmetic |
| Route | Topical |
| Notes | Delivered as a leave-on topical, not injected. |
Reconstitution
Supplied within finished topical products or as a cosmetic raw material, so injection reconstitution and syringe unit math do not apply.
Cautions
- A cosmetic ingredient, not an approved drug.
- Evidence is largely in vitro and formulation-based.
- Not intended for injection.
- Educational context only, not a usage recommendation.
Palmitoyl Tetrapeptide-7 FAQ
What is Palmitoyl Tetrapeptide-7?
A palmitoylated cosmetic peptide commonly cited in the skincare literature for context on soothing and anti-aging formulations.
How does Palmitoyl Tetrapeptide-7 work?
The palmitoyl tail improves lipid-layer penetration of the peptide. Reported to modulate interleukin signaling associated with skin inflammation. May support extracellular-matrix maintenance in skin models. Frequently combined with Palmitoyl Tripeptide-1 in blends.
What is Palmitoyl Tetrapeptide-7 used for?
Cosmetic anti-aging formulations; Soothing / anti-redness skincare; Skin-firmness appearance studies; Combination cosmetic peptide products.
What is a typical Palmitoyl Tetrapeptide-7 dose?
Typically formulated at very low percentages (parts-per-million range) in creams and serums, Applied once or twice daily as a cosmetic, Topical. This is a commonly cited figure for context only, not medical advice.
How do you reconstitute Palmitoyl Tetrapeptide-7?
Supplied within finished topical products or as a cosmetic raw material, so injection reconstitution and syringe unit math do not apply.
What is the half-life of Palmitoyl Tetrapeptide-7?
Not typically characterized; used topically rather than systemically.