Pulsatile release

Last updated August 2026

Hormone release in bursts rather than a steady stream. Growth hormone is released in pulses, which is why GH-secretagogue timing is discussed.

The body releases growth hormone in several bursts a day, with the largest typically arriving during early deep sleep. This is the reasoning behind timing GH-secretagogue doses, often before bed, to align with a natural pulse rather than flatten it. The pulse pattern concerns when a dose is taken, not how much is drawn; the units on the syringe still follow from the vial's concentration.

Educational reference only — not medical advice. Always follow the guidance of a qualified healthcare professional.